Two distinct phosphoinositide 3-kinases mediate polypeptide growth factor-stimulated PKB activation

Eight human isoforms of phosphoinositide 3-kinases (PI3Ks) exist, but their individual functions remain poorly understood. Here, we show that different human small cell lung carcinoma (SCLC) cell lines overexpress distinct subsets of class I(A) and II PI3Ks, which results in striking differences in...

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Detalles Bibliográficos

Publicado en:	EMBO J
Autores principales:	Arcaro, Alexandre, Khanzada, Umme K., Vanhaesebroeck, Bart, Tetley, Teresa D., Waterfield, Michael D., Seckl, Michael J.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Nature Publishing Group 2002
Materias:	Articles
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC129034/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12356726/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf512
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