Two distinct phosphoinositide 3-kinases mediate polypeptide growth factor-stimulated PKB activation

Eight human isoforms of phosphoinositide 3-kinases (PI3Ks) exist, but their individual functions remain poorly understood. Here, we show that different human small cell lung carcinoma (SCLC) cell lines overexpress distinct subsets of class I(A) and II PI3Ks, which results in striking differences in...

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Bibliografski detalji

Izdano u:	EMBO J
Glavni autori:	Arcaro, Alexandre, Khanzada, Umme K., Vanhaesebroeck, Bart, Tetley, Teresa D., Waterfield, Michael D., Seckl, Michael J.
Format:	Artigo
Jezik:	Inglês
Izdano:	Nature Publishing Group 2002
Teme:	Articles
Online pristup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC129034/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12356726/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf512
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