The potential of human regulatory T cells generated ex vivo as a treatment for lupus and other chronic inflammatory diseases

Regulatory T cells prevent autoimmunity by suppressing the reactivity of potentially aggressive self-reactive T cells. Contact-dependent CD4(+) CD25(+) 'professional' suppressor cells and other cytokine-producing CD4(+) and CD8(+) T-cell subsets mediate this protective function. Evidence w...

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Bibliographische Detailangaben
Hauptverfasser: Horwitz, David A, Gray, J Dixon, Zheng, Song Guo
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2002
Schlagworte:
Commentary
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC128930/
https://ncbi.nlm.nih.gov/pubmed/12106494
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