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Therapeutic Evaluation of Ex Vivo-Generated Versus Natural Regulatory T-cells in a Mouse Model of Chronic Gut Inflammation

The objectives of this study were to (a) evaluate and compare the ability of ex vivo-generated induced regulatory T cells (iTregs) and freshly isolated natural Tregs (nTregs) to reverse/attenuate preexisting intestinal inflammation in a mouse model of chronic colitis and (b) quantify the Tregtargete...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Karlsson, Fridrik, Martinez, Nicholas E., Gray, Laura, Zhang, Songlin, Tsunoda, Ikuo, Grisham, Matthew B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3812251/
https://ncbi.nlm.nih.gov/pubmed/23893082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MIB.0b013e31829c32dd
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