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The Frequency of Heteroplasmy in the HVII Region of mtDNA Differs across Tissue Types and Increases with Age

An immobilized sequence-specific oligonucleotide (SSO) probe system consisting of 16 SSO probes that detect sequence polymorphisms within five regions of the mtDNA control region was used to investigate the frequency of heteroplasmy in human mtDNA. Five regions of hypervariable region II (HVII) of t...

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Main Authors: Calloway, Cassandra D., Reynolds, Rebecca L., Herrin, Jr., George L., Anderson, Wyatt W.
格式: Artigo
語言:Inglês
出版: The American Society of Human Genetics 2000
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1288202/
https://ncbi.nlm.nih.gov/pubmed/10739761
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