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Multilocus Linkage Tests Based on Affected Relative Pairs

For complex diseases, recent interest has focused on methods that take into account joint effects at interacting loci. Conditioning on effects of disease loci at known locations can lead to increased power to detect effects at other loci. Moreover, use of joint models allows investigation of the eti...

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Bibliographic Details
Main Authors: Cordell, Heather J., Wedig, Geoffrey C., Jacobs, Kevin B., Elston, Robert C.
Format: Artigo
Language:Inglês
Published: The American Society of Human Genetics 2000
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1288194/
https://ncbi.nlm.nih.gov/pubmed/10729111
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