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The effect of TERC haploinsufficiency on the inheritance of telomere length
Telomeres protect chromosome ends from end-to-end fusion and degradation. Loss of telomere function causes cell-cycle arrest or cell death. Autosomal dominant dyskeratosis congenita (AD DC), a rare inherited bone marrow failure syndrome, is caused by mutations in TERC, the RNA component of telomeras...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1287981/ https://ncbi.nlm.nih.gov/pubmed/16284252 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0505318102 |
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