Variants near TERC are associated with mean telomere length.

We conducted genome-wide association analyses of mean leukocyte telomere length in 2,917 subjects and follow-up replication analyses in 9,492 and identified a locus on 3q26 encompassing the telomerase RNA component TERC, with compelling evidence for association (rs12696304, combined P value 3.72×10(...

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Main Authors: Codd, Veryan, Mangino, Massimo, van der Harst, Pim, Braund, Peter S, Kaiser, Michael, Beveridge, Alan J, Rafelt, Suzanne, Moore, Jasbir, Nelson, Chris, Soranzo, Nicole, Zhai, Guangju, Valdes, Ana M, Blackburn, Hannah, Leach, Irene Mateo, de Boer, Rudolf A, Goodall, Alison H, Ouwehand, Willem, van Veldhuisen, Dirk J., van Gilst, Wiek H., Navis, Gerjan, Burton, Paul R, Tobin, Martin D, Hall, Alistair S, Thompson, John R, Spector, Tim, Samani, Nilesh J
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773906/
https://ncbi.nlm.nih.gov/pubmed/20139977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.532
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