Variants near TERC are associated with mean telomere length.

We conducted genome-wide association analyses of mean leukocyte telomere length in 2,917 subjects and follow-up replication analyses in 9,492 and identified a locus on 3q26 encompassing the telomerase RNA component TERC, with compelling evidence for association (rs12696304, combined P value 3.72×10(...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Codd, Veryan, Mangino, Massimo, van der Harst, Pim, Braund, Peter S, Kaiser, Michael, Beveridge, Alan J, Rafelt, Suzanne, Moore, Jasbir, Nelson, Chris, Soranzo, Nicole, Zhai, Guangju, Valdes, Ana M, Blackburn, Hannah, Leach, Irene Mateo, de Boer, Rudolf A, Goodall, Alison H, Ouwehand, Willem, van Veldhuisen, Dirk J., van Gilst, Wiek H., Navis, Gerjan, Burton, Paul R, Tobin, Martin D, Hall, Alistair S, Thompson, John R, Spector, Tim, Samani, Nilesh J
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773906/
https://ncbi.nlm.nih.gov/pubmed/20139977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.532
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