Bactericidal Effect and Pharmacodynamics of Cethromycin (ABT-773) in a Murine Pneumococcal Pneumonia Model

Cethromycin (ABT-773), a new ketolide, possesses potent in vitro activity against Streptococcus pneumoniae. The objective of this study was to investigate the in vivo bactericidal activity of cethromycin against macrolide-susceptible and -resistant S. pneumoniae in a murine pneumonia model and to de...

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Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	Kim, Myo-Kyoung, Zhou, Wen, Tessier, Pamela R., Xuan, Dawei, Ye, Min, Nightingale, Charles H., Nicolau, David P.
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 2002
Sujets:	Experimental Therapeutics
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC128791/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12234843/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.10.3185-3192.2002
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