Bactericidal Effect and Pharmacodynamics of Cethromycin (ABT-773) in a Murine Pneumococcal Pneumonia Model

Cethromycin (ABT-773), a new ketolide, possesses potent in vitro activity against Streptococcus pneumoniae. The objective of this study was to investigate the in vivo bactericidal activity of cethromycin against macrolide-susceptible and -resistant S. pneumoniae in a murine pneumonia model and to de...

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Detalhes bibliográficos
Main Authors: Kim, Myo-Kyoung, Zhou, Wen, Tessier, Pamela R., Xuan, Dawei, Ye, Min, Nightingale, Charles H., Nicolau, David P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC128791/
https://ncbi.nlm.nih.gov/pubmed/12234843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.10.3185-3192.2002
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