Histone Deacetylase Inhibitors Enhance Candida albicans Sensitivity to Azoles and Related Antifungals: Correlation with Reduction in CDR and ERG Upregulation

Histone acetylation and deacetylation play important roles in eukaryotic gene regulation. Several histone deacetylase (HDA) inhibitors have been characterized, including trichostatin A (TSA), apicidin, and sodium butyrate. We tested their effects on Candida albicans in vitro growth, heat sensitivity...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Smith, W. Lamar, Edlind, Thomas D.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2002
Assuntos:	Mechanisms of Resistance
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC128736/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12384361/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.11.3532-3539.2002
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