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Congenital Hereditary Lymphedema Caused by a Mutation That Inactivates VEGFR3 Tyrosine Kinase

Hereditary lymphedema is a chronic swelling of limbs due to dysfunction of lymphatic vessels. An autosomal dominant, congenital form of the disease, also known as “Milroy disease,” has been mapped to the telomeric part of chromosome 5q, in the region 5q34-q35. This region contains a good candidate g...

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Detalhes bibliográficos
Main Authors: Irrthum, Alexandre, Karkkainen, Marika J., Devriendt, Koen, Alitalo, Kari, Vikkula, Miikka
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Human Genetics 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1287178/
https://ncbi.nlm.nih.gov/pubmed/10856194
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