Mutations in the VEGFR3 Signaling Pathway Explain 36% of Familial Lymphedema

Lymphedema is caused by dysfunction of lymphatic vessels, leading to disabling swelling that occurs mostly on the extremities. Lymphedema can be either primary (congenital) or secondary (acquired). Familial primary lymphedema commonly segregates in an autosomal dominant or recessive manner. It can a...

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Detalles Bibliográficos
Autores principales: Mendola, A., Schlögel, M.J., Ghalamkarpour, A., Irrthum, A., Nguyen, H.L., Fastré, E., Bygum, A., van der Vleuten, C., Fagerberg, C., Baselga, E., Quere, I., Mulliken, J.B., Boon, L.M., Brouillard, P., Vikkula, M.
Formato: Artigo
Lenguaje:Inglês
Publicado: S. Karger AG 2013
Materias:
Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3776465/
https://ncbi.nlm.nih.gov/pubmed/24167460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000354097
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