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Testing Linkage Disequilibrium in Sibships

We describe the use of multivariate regression for testing allelic association in the presence of linkage, using marker genotype data from sibships. The test is valid, provided that the correct mean structure is modeled but does not require the correlation structure within families to be specified....

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Bibliografiske detaljer
Main Authors: Siegmund, Kimberly D., Langholz, Bryan, Kraft, Peter, Thomas, Duncan C.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society of Human Genetics 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1287084/
https://ncbi.nlm.nih.gov/pubmed/10831398
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