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A discordant-sibship test for disequilibrium and linkage: no need for parental data.

The sibship disequilibrium test (SDT) is designed to detect both linkage in the presence of association and association in the presence of linkage (linkage disequilibrium). The test does not require parental data but requires discordant sibships with at least one affected and one unaffected sibling....

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Bibliographic Details
Main Authors: Horvath, S, Laird, N M
Format: Artigo
Language:Inglês
Published: 1998
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1377659/
https://ncbi.nlm.nih.gov/pubmed/9837840
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