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A sibship test for linkage in the presence of association: the sib transmission/disequilibrium test.

Linkage analysis with genetic markers has been successful in the localization of genes for many monogenic human diseases. In studies of complex diseases, however, tests that rely on linkage disequilibrium (the simultaneous presence of linkage and association) are often more powerful than those that...

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Bibliografiske detaljer
Main Authors: Spielman, R S, Ewens, W J
Format: Artigo
Sprog:Inglês
Udgivet: 1998
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1376890/
https://ncbi.nlm.nih.gov/pubmed/9463321
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