Stampidine Is a Potent Inhibitor of Zidovudine- and Nucleoside Analog Reverse Transcriptase Inhibitor-Resistant Primary Clinical Human Immunodeficiency Virus Type 1 Isolates with Thymidine Analog Mutations

We report the antiretroviral activity of stavudine-5′-(p-bromophenyl methoxyalaninyl phosphate) (stampidine [STAMP]), a novel aryl phosphate derivative of stavudine, against primary clinical human immunodeficiency virus type 1 (HIV-1) isolates. STAMP inhibited each one of nine clinical HIV-1 isolate...

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Detalhes bibliográficos
Main Authors: Uckun, Fatih M., Pendergrass, Sharon, Venkatachalam, T. K., Qazi, Sanjive, Richman, Douglas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC128707/
https://ncbi.nlm.nih.gov/pubmed/12384373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.11.3613-3616.2002
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