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Identification of thrombospondin 1 (TSP-1) as a novel mediator of cell injury in kidney ischemia
Thrombospondin 1 (TSP-1) is a matricellular protein that inhibits angiogenesis and causes apoptosis in vivo and in vitro in several cancerous cells and tissues. Here we identify TSP-1 as the molecule with the highest induction level at 3 hours of IR injury in rat and mouse kidneys subjected to ische...
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| Hauptverfasser: | , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Clinical Investigation
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1283940/ https://ncbi.nlm.nih.gov/pubmed/16294224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI25461 |
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