Identification of thrombospondin 1 (TSP-1) as a novel mediator of cell injury in kidney ischemia

Thrombospondin 1 (TSP-1) is a matricellular protein that inhibits angiogenesis and causes apoptosis in vivo and in vitro in several cancerous cells and tissues. Here we identify TSP-1 as the molecule with the highest induction level at 3 hours of IR injury in rat and mouse kidneys subjected to ische...

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Detalhes bibliográficos
Main Authors: Thakar, Charuhas V., Zahedi, Kamyar, Revelo, Monica P., Wang, Zhaohui, Burnham, Charles E., Barone, Sharon, Bevans, Shannon, Lentsch, Alex B., Rabb, Hamid, Soleimani, Manoocher
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2005
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1283940/
https://ncbi.nlm.nih.gov/pubmed/16294224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI25461
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