A model of anthrax toxin lethal factor bound to protective antigen

Anthrax toxin is made up of three proteins: the edema factor (EF), lethal factor (LF) enzymes, and the multifunctional protective antigen (PA). Proteolytically activated PA heptamerizes, binds the EF/LF enzymes, and forms a pore that allows for EF/LF passage into host cells. Using directed mutagenes...

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Autores principales: Lacy, D. Borden, Lin, Henry C., Melnyk, Roman A., Schueler-Furman, Ora, Reither, Laura, Cunningham, Kristina, Baker, David, Collier, R. John
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2005
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1283467/
https://ncbi.nlm.nih.gov/pubmed/16251269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0508259102
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