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Coadministration of an Interleukin-12 Gene and a Trypanosoma cruzi Gene Improves Vaccine Efficacy

We tested the immunogenicity of two Trypanosoma cruzi antigens injected into mice in the form of DNA vaccine. Immunization with DNA encoding dihydroorotate dehydrogenase did not confer protective immunity in all mouse strains tested. Immunization with DNA encoding trans-sialidase surface antigen (TS...

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Bibliografische Detailangaben
Veröffentlicht in:Infect Immun
Hauptverfasser: Katae, Masaharu, Miyahira, Yasushi, Takeda, Kazuyoshi, Matsuda, Hironori, Yagita, Hideo, Okumura, Ko, Takeuchi, Tsutomu, Kamiyama, Tsuneo, Ohwada, Akihiko, Fukuchi, Yoshinosuke, Aoki, Takashi
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2002
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC128276/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12183527/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.70.9.4833-4840.2002
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