Coadministration of an Interleukin-12 Gene and a Trypanosoma cruzi Gene Improves Vaccine Efficacy

We tested the immunogenicity of two Trypanosoma cruzi antigens injected into mice in the form of DNA vaccine. Immunization with DNA encoding dihydroorotate dehydrogenase did not confer protective immunity in all mouse strains tested. Immunization with DNA encoding trans-sialidase surface antigen (TS...

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Autori principali: Katae, Masaharu, Miyahira, Yasushi, Takeda, Kazuyoshi, Matsuda, Hironori, Yagita, Hideo, Okumura, Ko, Takeuchi, Tsutomu, Kamiyama, Tsuneo, Ohwada, Akihiko, Fukuchi, Yoshinosuke, Aoki, Takashi
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2002
Soggetti:
Fungal and Parasitic Infections
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC128276/
https://ncbi.nlm.nih.gov/pubmed/12183527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.9.4833-4840.2002
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