Coadministration of an Interleukin-12 Gene and a Trypanosoma cruzi Gene Improves Vaccine Efficacy

We tested the immunogenicity of two Trypanosoma cruzi antigens injected into mice in the form of DNA vaccine. Immunization with DNA encoding dihydroorotate dehydrogenase did not confer protective immunity in all mouse strains tested. Immunization with DNA encoding trans-sialidase surface antigen (TS...

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Detalhes bibliográficos
Main Authors: Katae, Masaharu, Miyahira, Yasushi, Takeda, Kazuyoshi, Matsuda, Hironori, Yagita, Hideo, Okumura, Ko, Takeuchi, Tsutomu, Kamiyama, Tsuneo, Ohwada, Akihiko, Fukuchi, Yoshinosuke, Aoki, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC128276/
https://ncbi.nlm.nih.gov/pubmed/12183527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.9.4833-4840.2002
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