Coadministration of an Interleukin-12 Gene and a Trypanosoma cruzi Gene Improves Vaccine Efficacy

We tested the immunogenicity of two Trypanosoma cruzi antigens injected into mice in the form of DNA vaccine. Immunization with DNA encoding dihydroorotate dehydrogenase did not confer protective immunity in all mouse strains tested. Immunization with DNA encoding trans-sialidase surface antigen (TS...

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Detalles Bibliográficos
Autores principales: Katae, Masaharu, Miyahira, Yasushi, Takeda, Kazuyoshi, Matsuda, Hironori, Yagita, Hideo, Okumura, Ko, Takeuchi, Tsutomu, Kamiyama, Tsuneo, Ohwada, Akihiko, Fukuchi, Yoshinosuke, Aoki, Takashi
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2002
Materias:
Fungal and Parasitic Infections
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC128276/
https://ncbi.nlm.nih.gov/pubmed/12183527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.9.4833-4840.2002
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