Enhancement of Protective Efficacy following Intranasal Immunization with Vaccine Plus a Nontoxic LTK63 Mutant Delivered with Nanoparticles

Most vaccines are still given parenterally. Mucosal vaccination would offer different advantages over parenteral immunization, including blocking of the pathogens at the portal of entry. In this paper, nontoxic Escherichia coli heat-labile enterotoxin (LT) mutants and Supramolecular Biovector system...

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Detalhes bibliográficos
Main Authors: Baudner, B. C., Balland, O., Giuliani, M. M., Von Hoegen, P., Rappuoli, R., Betbeder, D., Del Giudice, G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC128246/
https://ncbi.nlm.nih.gov/pubmed/12183520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.9.4785-4790.2002
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