Enhancement of Protective Efficacy following Intranasal Immunization with Vaccine Plus a Nontoxic LTK63 Mutant Delivered with Nanoparticles

Most vaccines are still given parenterally. Mucosal vaccination would offer different advantages over parenteral immunization, including blocking of the pathogens at the portal of entry. In this paper, nontoxic Escherichia coli heat-labile enterotoxin (LT) mutants and Supramolecular Biovector system...

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Autori principali: Baudner, B. C., Balland, O., Giuliani, M. M., Von Hoegen, P., Rappuoli, R., Betbeder, D., Del Giudice, G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2002
Soggetti:
Microbial Immunity and Vaccines
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC128246/
https://ncbi.nlm.nih.gov/pubmed/12183520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.9.4785-4790.2002
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