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Immunogenicity in a Mouse Model of a Conjugate Vaccine Made with a Synthetic Single Repeating Unit of Type 14 Pneumococcal Polysaccharide Coupled to CRM197

Oligosaccharides (OSs) related to the pneumococcal type 14 capsular polysaccharide (Pn14PS) were studied for their ability to inhibit the binding between anti-PS14 antisera and native PS14. A synthetic tetrasaccharide corresponding to the repeating unit of the Pn14PS, a hexasaccharide mimic, and an...

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Autori principali: Mawas, Fatme, Niggemann, Jutta, Jones, Christopher, Corbel, Michael J., Kamerling, Johannis P., Vliegenthart, Johannes F. G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC128223/
https://ncbi.nlm.nih.gov/pubmed/12183560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.9.5107-5114.2002
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