Immunogenicity in a Mouse Model of a Conjugate Vaccine Made with a Synthetic Single Repeating Unit of Type 14 Pneumococcal Polysaccharide Coupled to CRM197

Oligosaccharides (OSs) related to the pneumococcal type 14 capsular polysaccharide (Pn14PS) were studied for their ability to inhibit the binding between anti-PS14 antisera and native PS14. A synthetic tetrasaccharide corresponding to the repeating unit of the Pn14PS, a hexasaccharide mimic, and an...

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Detalhes bibliográficos
Main Authors: Mawas, Fatme, Niggemann, Jutta, Jones, Christopher, Corbel, Michael J., Kamerling, Johannis P., Vliegenthart, Johannes F. G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC128223/
https://ncbi.nlm.nih.gov/pubmed/12183560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.9.5107-5114.2002
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