Susceptibility of Interleukin-2-Deficient Mice to Toxoplasma gondii Is Associated with a Defect in the Production of Gamma Interferon

Costimulation through the B7-CD28 interaction is an important second signal for T-cell activation, and previous studies have shown that CD28(−/−) mice infected with Toxoplasma gondii generate suboptimal CD4(+) T-cell responses, associated with a defect in production of the T-cell growth factor inter...

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Detalhes bibliográficos
Main Authors: Villegas, Eric N., Lieberman, Linda A., Carding, Simon R., Hunter, Christopher A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC128219/
https://ncbi.nlm.nih.gov/pubmed/12183516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.9.4757-4761.2002
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