Susceptibility of Interleukin-2-Deficient Mice to Toxoplasma gondii Is Associated with a Defect in the Production of Gamma Interferon

Costimulation through the B7-CD28 interaction is an important second signal for T-cell activation, and previous studies have shown that CD28(−/−) mice infected with Toxoplasma gondii generate suboptimal CD4(+) T-cell responses, associated with a defect in production of the T-cell growth factor inter...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Villegas, Eric N., Lieberman, Linda A., Carding, Simon R., Hunter, Christopher A.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2002
Assuntos:	Fungal and Parasitic Infections
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC128219/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12183516/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.70.9.4757-4761.2002
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