A mutation in the pore of the sodium channel alters gating.

Ion permeation and channel gating are classically considered independent processes, but site-specific mutagenesis studies in K channels suggest that residues in or near the ion-selective pore of the channel can influence activation and inactivation. We describe a mutation in the pore of the skeletal...

Full description

Saved in:
Bibliographic Details
Main Authors: Tomaselli, G F, Chiamvimonvat, N, Nuss, H B, Balser, J R, Pérez-García, M T, Xu, R H, Orias, D W, Backx, P H, Marban, E
Format: Artigo
Language:Inglês
Published: 1995
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1282084/
https://ncbi.nlm.nih.gov/pubmed/7612823
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items