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Peptide design in machina: development of artificial mitochondrial protein precursor cleavage sites by simulated molecular evolution.

Artificial neural networks were used for extraction of characteristic physiochemical features from mitochondrial matrix metalloprotease target sequences. The amino acid properties hydrophobicity and volume were used for sequence encoding. A window of 12 residues was employed, encompassing positions...

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Bibliografiske detaljer
Main Authors: Schneider, G, Schuchhardt, J, Wrede, P
Format: Artigo
Sprog:Inglês
Udgivet: 1995
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1281708/
https://ncbi.nlm.nih.gov/pubmed/7696497
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