Immunization with a Polyprotein Vaccine Consisting of the T-Cell Antigens Thiol-Specific Antioxidant, Leishmania major Stress-Inducible Protein 1, and Leishmania Elongation Initiation Factor Protects against Leishmaniasis

Development of an effective vaccine against Leishmania infection is a priority of tropical disease research. We have recently demonstrated protection against Leishmania major in the murine and nonhuman primate models with individual or combinations of purified leishmanial recombinant antigens delive...

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Main Authors: Coler, Rhea N., Skeiky, Yasir A. W., Bernards, Karen, Greeson, Kay, Carter, Darrick, Cornellison, Charisa D., Modabber, Farrokh, Campos-Neto, Antonio, Reed, Steven G.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2002
Teme:
Microbial Immunity and Vaccines
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC128156/
https://ncbi.nlm.nih.gov/pubmed/12117930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.8.4215-4225.2002
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