Proteasomal Degradation of Cytotoxic Necrotizing Factor 1-Activated Rac

The cytotoxic necrotizing factor 1 (CNF1) from Escherichia coli has been shown to activate members of the Rho family by deamidation of glutamine 63. This amino acid is essential for hydrolysis of GTP, and any substitution results in a constitutively active Rho. Activation of Rho induces the formatio...

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Hlavní autoři: Lerm, Maria, Pop, Marius, Fritz, Gerhard, Aktories, Klaus, Schmidt, Gudula
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2002
Témata:
Molecular Pathogenesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC128152/
https://ncbi.nlm.nih.gov/pubmed/12117911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.8.4053-4058.2002
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