Proteasomal Degradation of Cytotoxic Necrotizing Factor 1-Activated Rac

The cytotoxic necrotizing factor 1 (CNF1) from Escherichia coli has been shown to activate members of the Rho family by deamidation of glutamine 63. This amino acid is essential for hydrolysis of GTP, and any substitution results in a constitutively active Rho. Activation of Rho induces the formatio...

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Detalhes bibliográficos
Main Authors: Lerm, Maria, Pop, Marius, Fritz, Gerhard, Aktories, Klaus, Schmidt, Gudula
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Molecular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC128152/
https://ncbi.nlm.nih.gov/pubmed/12117911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.8.4053-4058.2002
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