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Proteasomal Degradation of Cytotoxic Necrotizing Factor 1-Activated Rac
The cytotoxic necrotizing factor 1 (CNF1) from Escherichia coli has been shown to activate members of the Rho family by deamidation of glutamine 63. This amino acid is essential for hydrolysis of GTP, and any substitution results in a constitutively active Rho. Activation of Rho induces the formatio...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2002
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC128152/ https://ncbi.nlm.nih.gov/pubmed/12117911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.8.4053-4058.2002 |
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