Dissemination of Mycobacterium tuberculosis Is Influenced by Host Factors and Precedes the Initiation of T-Cell Immunity

We report that dissemination of Mycobacterium tuberculosis in the mouse is under host control and precedes the initiation of T-cell immunity. Nine to eleven days after aerosol inoculation, M. tuberculosis disseminates to the pulmonary lymph nodes (LN), where M. tuberculosis-specific T cells are dete...

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Detalhes bibliográficos
Main Authors: Chackerian, Alissa A., Alt, Jennifer M., Perera, Thushara V., Dascher, Christopher C., Behar, Samuel M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC128141/
https://ncbi.nlm.nih.gov/pubmed/12117962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.8.4501-4509.2002
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