Nitric Oxide-Mediated Proteasome-Dependent Oligonucleosomal DNA Fragmentation in Leishmania amazonensis Amastigotes

Resistance to leishmanial infections depends on intracellular parasite killing by activated host macrophages through the l-arginine-nitric oxide (NO) metabolic pathway. Here we investigate the cell death process induced by NO for the intracellular protozoan Leishmania amazonensis. Exposure of amasti...

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Bibliographische Detailangaben
Hauptverfasser: Holzmuller, Philippe, Sereno, Denis, Cavaleyra, Mireille, Mangot, Isabelle, Daulouede, Sylvie, Vincendeau, Philippe, Lemesre, Jean-Loup
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2002
Schlagworte:
Fungal and Parasitic Infections
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC128075/
https://ncbi.nlm.nih.gov/pubmed/12065515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.7.3727-3735.2002
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