Construction, Characterization, and Animal Testing of WRSd1, a Shigella dysenteriae 1 Vaccine

WRSd1 is a Shigella dysenteriae 1 vaccine containing deletions of the virG(icsA) gene required for intercellular spreading and a 20-kb chromosomal region encompassing the Shiga toxin genes (stxAB). WRSd1 was constructed from S. dysenteriae 1 strain 1617 that was originally isolated during the 1968 t...

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Detalhes bibliográficos
Main Authors: Venkatesan, Malabi M., Hartman, Antoinette B., Newland, John W., Ivanova, Vessela S., Hale, Thomas L., McDonough, Marie, Butterton, Joan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC128025/
https://ncbi.nlm.nih.gov/pubmed/12010984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.6.2950-2958.2002
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