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Enhanced Delivery of Exogenous Peptides into the Class I Antigen Processing and Presentation Pathway

Current immunization strategies, using peptide or protein antigens, generally fail to elicit cytotoxic-T-lymphocyte responses, since these antigens are unable to access intracellular compartments where loading of major histocompatibility complex class I (MHC-I) molecules occurs. In an attempt to cir...

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Autori principali: de Haan, Lolke, Hearn, Arron R., Rivett, A. Jennifer, Hirst, Timothy R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC128024/
https://ncbi.nlm.nih.gov/pubmed/12011020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.6.3249-3258.2002
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