Intracellular Delivery of a Cytolytic T-Lymphocyte Epitope Peptide by Pertussis Toxin to Major Histocompatibility Complex Class I without Involvement of the Cytosolic Class I Antigen Processing Pathway

A CD8(+) cytolytic T-lymphocyte (CTL) response to antigen-presenting cells generally requires intracellular delivery or synthesis of antigens in order to access the major histocompatibility complex (MHC) class I processing and presentation pathway. To test the ability of pertussis toxin (PT) to deli...

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Detalhes bibliográficos
Main Authors: Carbonetti, Nicholas H., Irish, Teresa J., Chen, Carrie H., O’Connell, Colin B., Hadley, Gregg A., McNamara, Ulrike, Tuskan, Robert G., Lewis, George K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC96361/
https://ncbi.nlm.nih.gov/pubmed/9916065
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