The Human DEK Proto-Oncogene Is a Senescence Inhibitor and an Upregulated Target of High-Risk Human Papillomavirus E7

The human DEK proto-oncogene is a nucleic acid binding protein with suspected roles in human carcinogenesis, autoimmune disease, and viral infection. Intracellular DEK functions, however, are poorly understood. In papillomavirus-positive cervical cancer cells, downregulation of viral E6/E7 oncogene...

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Main Authors: Wise-Draper, Trisha M., Allen, Hillary V., Thobe, Megan N., Jones, Elizabeth E., Habash, Kristen B., Münger, Karl, Wells, Susanne I.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2005
Assuntos:
Transformation and Oncogenesis
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1280217/
https://ncbi.nlm.nih.gov/pubmed/16254365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.22.14309-14317.2005
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