DEK Proto-Oncogene Expression Interferes with the Normal Epithelial Differentiation Program

Overexpression of the DEK gene is associated with multiple human cancers, but its specific roles as a putative oncogene are not well defined. DEK transcription was previously shown to be induced by the high-risk human papillomavirus (HPV) E7 oncogene via E2F and Rb pathways. Transient DEK overexpres...

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Autori principali: Wise-Draper, Trisha M., Morreale, Richard J., Morris, Teresa A., Mintz-Cole, Rachael A., Hoskins, Elizabeth E., Balsitis, Scott J., Husseinzadeh, Nader, Witte, David P., Wikenheiser-Brokamp, Kathryn A., Lambert, Paul F., Wells, Susanne I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2009
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Regular Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2631320/
https://ncbi.nlm.nih.gov/pubmed/19036808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080330
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