Effect of Alternating Passage on Adaptation of Sindbis Virus to Vertebrate and Invertebrate Cells

Mosquito-borne alphaviruses, which replicate alternately and obligately in mosquitoes and vertebrates, appear to experience lower rates of evolution than do many RNA viruses that replicate solely in vertebrates. This genetic stability is hypothesized to result from the alternating host cycle, which...

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Detalhes bibliográficos
Main Authors: Greene, Ivorlyne P., Wang, Eryu, Deardorff, Eleanor R., Milleron, Rania, Domingo, Esteban, Weaver, Scott C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Genetic Diversity and Evolution
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1280187/
https://ncbi.nlm.nih.gov/pubmed/16254360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.22.14253-14260.2005
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