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Genetic and Fitness Changes Accompanying Adaptation of an Arbovirus to Vertebrate and Invertebrate Cells

The alternating host cycle and persistent vector infection may constrain the evolution of arboviruses. To test this hypothesis, eastern equine encephalitis virus was passaged in BHK or mosquito cells, as well as in alternating (both) host cell passages. High and low multiplicities were used to exami...

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Bibliografiske detaljer
Main Authors: Weaver, Scott C., Brault, Aaron C., Kang, Wenli, Holland, John J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 1999
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC104213/
https://ncbi.nlm.nih.gov/pubmed/10196330
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