Viral Protein VP4 Is a Target of Human Antibodies Enhancing Coxsackievirus B4- and B3-Induced Synthesis of Alpha Interferon

Coxsackievirus B4 (CVB4)-induced production of alpha interferon (IFN-α) by peripheral blood mononuclear cells (PBMC) is enhanced in vitro by nonneutralizing anti-CVB4 antibodies from healthy subjects and, to a higher extent, from patients with insulin-dependent diabetes mellitus. In this study, we f...

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Autori principali: Chehadeh, Wassim, Lobert, Pierre-Emmanuel, Sauter, Pierre, Goffard, Anne, Lucas, Bernadette, Weill, Jacques, Vantyghem, Marie-Christine, Alm, Gunnar, Pigny, Pascal, Hober, Didier
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2005
Soggetti:
Pathogenesis and Immunity
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1280186/
https://ncbi.nlm.nih.gov/pubmed/16254324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.22.13882-13891.2005
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