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Persistent Infection of Human Pancreatic Islets by Coxsackievirus B Is Associated with Alpha Interferon Synthesis in β Cells

The interactions of coxsackievirus B3 (CVB3), CVB4E2 (diabetogenic), and CVB4JBV (nondiabetogenic) strains with human pancreatic islets from eight adult brain-dead donors were investigated. Persistent replication of viruses in human islets was proved by detection of viral RNA by in situ hybridizatio...

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Bibliografiske detaljer
Main Authors: Chehadeh, Wassim, Kerr-Conte, Julie, Pattou, François, Alm, Gunar, Lefebvre, Jean, Wattré, Pierre, Hober, Didier
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC102054/
https://ncbi.nlm.nih.gov/pubmed/11024144
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