Persistent Infection of Thymic Epithelial Cells with Coxsackievirus B4 Results in Decreased Expression of Type 2 Insulin-Like Growth Factor

It has been hypothesized that a disturbance of central self-tolerance to islet β cells may play a role in the enteroviral pathogenesis of type 1 diabetes. Whether enteroviruses can induce an impaired expression of β-cell self-antigens in thymic epithelial cells has been investigated in a murine thym...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jaïdane, Hela, Caloone, Delphine, Lobert, Pierre-Emmanuel, Sane, Famara, Dardenne, Olivier, Naquet, Philippe, Gharbi, Jawhar, Aouni, Mahjoub, Geenen, Vincent, Hober, Didier
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2012
Schlagworte:
Virus-Cell Interactions
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457166/
https://ncbi.nlm.nih.gov/pubmed/22855493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00726-12
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