Dissociated Linkage of Cytokine-Inducing Activity and Cytotoxicity to Different Domains of Listeriolysin O from Listeria monocytogenes

Listeriolysin O (LLO), a cholesterol-binding cytolysin of Listeria monocytogenes, exhibits cytokine-inducing and cytolytic activities. Because the cytolytic activity was abolished by cholesterol treatment but the cytokine-inducing activity was not, these activities appeared to be linked to different...

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Опубліковано в::	Infect Immun
Автори:	Kohda, Chikara, Kawamura, Ikuo, Baba, Hisashi, Nomura, Takamasa, Ito, Yutaka, Kimoto, Terumi, Watanabe, Isao, Mitsuyama, Masao
Формат:	Artigo
Мова:	Inglês
Опубліковано:	American Society for Microbiology (ASM) 2002
Предмети:	Host Response and Inflammation
Онлайн доступ:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127785/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11854218/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.70.3.1334-1341.2002
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