Dissociated Linkage of Cytokine-Inducing Activity and Cytotoxicity to Different Domains of Listeriolysin O from Listeria monocytogenes

Listeriolysin O (LLO), a cholesterol-binding cytolysin of Listeria monocytogenes, exhibits cytokine-inducing and cytolytic activities. Because the cytolytic activity was abolished by cholesterol treatment but the cytokine-inducing activity was not, these activities appeared to be linked to different...

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Autori principali: Kohda, Chikara, Kawamura, Ikuo, Baba, Hisashi, Nomura, Takamasa, Ito, Yutaka, Kimoto, Terumi, Watanabe, Isao, Mitsuyama, Masao
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2002
Soggetti:
Host Response and Inflammation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC127785/
https://ncbi.nlm.nih.gov/pubmed/11854218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.3.1334-1341.2002
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