A trial of somatic gene targeting in vivo with an adenovirus vector

BACKGROUND: Gene targeting in vivo provides a potentially powerful method for gene analysis and gene therapy. In order to sensitively detect and accurately measure designed sequence changes, we have used a transgenic mouse system, MutaMouse, which has been developed for detection of mutation in vivo...

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Bibliografiske detaljer
Main Authors: Ino, Asami, Naito, Yasuhiro, Mizuguchi, Hiroyuki, Handa, Naofumi, Hayakawa, Takao, Kobayashi, Ichizo
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2005
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1277836/
https://ncbi.nlm.nih.gov/pubmed/16219108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-0556-3-8
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