DNA Adenine Methylase Overproduction in Yersinia pseudotuberculosis Alters YopE Expression and Secretion and Host Immune Responses to Infection

Yersinia pseudotuberculosis mutants that overproduce the DNA adenine methylase (Dam) are highly attenuated, confer fully protective immune responses, and secrete several Yersinia virulence proteins (Yersinia outer proteins [Yops]) under conditions that are nonpermissive for secretion in wild-type st...

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Autores principales: Julio, Steven M., Heithoff, Douglas M., Sinsheimer, Robert L., Low, David A., Mahan, Michael J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2002
Materias:
Host Response and Inflammation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC127708/
https://ncbi.nlm.nih.gov/pubmed/11796641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.2.1006-1009.2002
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