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DNA Adenine Methylase Overproduction in Yersinia pseudotuberculosis Alters YopE Expression and Secretion and Host Immune Responses to Infection

Yersinia pseudotuberculosis mutants that overproduce the DNA adenine methylase (Dam) are highly attenuated, confer fully protective immune responses, and secrete several Yersinia virulence proteins (Yersinia outer proteins [Yops]) under conditions that are nonpermissive for secretion in wild-type st...

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Bibliografiske detaljer
Main Authors: Julio, Steven M., Heithoff, Douglas M., Sinsheimer, Robert L., Low, David A., Mahan, Michael J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC127708/
https://ncbi.nlm.nih.gov/pubmed/11796641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.2.1006-1009.2002
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